The effect of vitamin A on development and differentiation of oral armature with particular reference of Bufo melanostictus (schneider) tadpoles of stage 34 and 36 of this toad species. Vitamin A has been found to affect differentiation of oral armature in the toad tadpoles and the effect is more severe on younger tadpoles as compared to the older ones. In stage 34 and 36 untreated group shows well developed keratinized oral armature. Vitamin A treatment has been found to inhibit differentiation of oral armature and degeneration of horny denticles. Tadpoles of discontinuous treated group shows well recovery from the degenerating effect of vitamin A. Horny teeth and jaws are visible in mouth region of these tadpoles.