Assessment of Toxic Effect of Dibutyl Phthalate (DBP) on Acid and Alkaline Phosphatase in Goldfish (Carassius auratus) With Ameliorative Efficacy of Withania somnifera
DOI:
https://doi.org/10.59436/jsiane.210.2583-2093Keywords:
Liver enzymes, Gold fish, Dibutyl Phthalate, Withania somniferaAbstract
This study explores the metabolic responses of goldfish (Carassius auratus) to dibutyl phthalate (DBP) exposure, emphasizing the therapeutic potential of Withania somnifera (Ashwagandha). DBP, a prevalent environmental pollutant and endocrine disruptor, is commonly found in plastics and personal care products, leading to significant contamination of aquatic ecosystems. The objective of this research is to assess the impact of DBP on the metabolic health of goldfish and evaluate the efficacy of Withania somnifera in mitigating DBP-induced metabolic disturbances. Following DBP exposure, groups of goldfish were treated with Withania somnifera extracts. The therapeutic efficiency of Withania somnifera was evaluated by comparing metabolic parameters of the treated groups with those of the DBP-only exposed group and a control group. Treatment with Withania somnifera showed significant amelioration of these effects, with treated fish exhibiting enzyme activities closer to those of the control group. This study highlights the detrimental impact of DBP on the health of goldfish and underscores the potential of Withania somnifera as a therapeutic agent in counteracting these effects. These findings suggest promising applications of Withania somnifera in environmental toxicology and the preservation of aquatic organism health.
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