Investigation of extracts from the medicinal plant Emblica officinalis for their preventive properties against cisplatin-induced toxicity
DOI:
https://doi.org/10.59436/jsiane.299.2583-2093Keywords:
Emblica officinalis, medicinal plants, cisplatin-induced toxicity, extractsAbstract
The study assesses the efficacy of medicinal plant extracts in mitigating the toxicity induced by cisplatin. A widely used cancer treatment, cisplatin is associated with severe adverse effects. Investigate the preventative properties of extracts derived from medicinal plants against these adverse effects. Assays will be conducted in vitro and potentially in vivo to determine whether or not these plant extracts can mitigate the toxicity induced by cisplatin in cells and animals. Organ function, cell viability, and oxidative stress indicators may be utilized to assess the protective effects of plant extracts. This research may aid in the development of supplementary medications that reduce the toxicity induced by cisplatin, thereby enhancing the efficacy and acceptability of cancer therapy. Bioactive component extraction from the leaves of medicinal plants, Emblica officinalis. The aim of this research is to investigate the protective effect of medicinal plants originating in the Chhattisgarh region against cisplatin-induced nephrotoxicity. Anti-cancer properties have been empirically demonstrated in these plants.
References
Asmawi, M. Z., Kankaanranta, H., Moilanen, E., & Vapaatalo, H. (1993). Anti‐inflammatory activities of Emblica officinalis Gaertn leaf extracts. Journal of Pharmacy and Pharmacology, 45(6), 581-584. DOI: https://doi.org/10.1111/j.2042-7158.1993.tb05605.x
Badarinath, A. V., Rao, K. M., Chetty, C. M. S., Ramkanth, S., Rajan, T. V. S., & Gnanaprakash, K. (2010). A review on in-vitro antioxidant methods: comparisions, correlations and considerations. International Journal of PharmTech Research, 2(2), 1276-1285.
Bahmani, M., Baharvand-Ahmadi, B., Tajeddini, P., Rafieian-Kopaei, M., & Naghdi, N. (2016). Identification of medicinal plants for the treatment of kidney and urinary stones. Journal of renal injury prevention, 5(3), 129-133. DOI: https://doi.org/10.15171/jrip.2016.27
Lakshmi, M. S., Reddy, U. K., & Rani, S. R. K. S. (2012). A review on medicinal plants for nephroprotective activity. Asian Journal of Pharmaceutical and Clinical Research. 5(4), 8-14.
Moilanen, E. (1997). Anti-Inflammatory Activity of Extracts lirom Leaves of Phyllanthus emblica. Planta medica, 63, 518-524. DOI: https://doi.org/10.1055/s-2006-957754
Nain, P., Saini, V., & Sharma, S. (2012a). In-vitro antibacterial and antioxidant activity of Emblica officinalis leaves extract. International Journal of Pharmacy and Pharmaceutical Sciences, 4(1), 385-389.
Nain, P., Saini, V., Sharma, S., & Nain, J. (2012b). Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin- induced type-2 diabetes mellitus (T2DM) rats. Journal of Ethnopharmacology, 142(1), 65-71. DOI: https://doi.org/10.1016/j.jep.2012.04.014
Ritesh J. and Sanmati K. J. (2010). Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview. International Journal of Phytomedicine, 2, 186-196.
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