Qualitative Analysis of Crude Extract from the Leaves of Cassia occidentalis
DOI:
https://doi.org/10.59436/jsiane.196.2583-2093Keywords:
Cassia occidentalis, Crude Extract, Leaves, Qualitative Analysis, antioxidants, anticancer agents, Medicinal plantsAbstract
Medicinal plants have intrinsic antioxidant qualities that these items use to enhance health, prevent sickness, and prolonged life expectancy. In this study, a preliminary study of qualitative analysis was performed in crude extracts of leaf extracts of Cassia occidentalis using various solvent on the basis of polarity. The data obtained in the in vitro models clearly establish the antioxidant potency of leaf extracts of Cassia occidentalis. In the present study we have used aqueous extract of the leaves, followed by the methanolic, disteled water and petroleum ether extracts, respectively. We have reported the presence of carbohydrates, alkaloids, phenols, tannins, phytosterols, and flavonoids through a series of standard tests. The study provides substantial evidence supporting the therapeutic potential of Cassia extract, as sources of various natural antioxidants and anticancer agents. The exploration of these plant extract could potentially lead to the development of new, effective, and natural therapeutic agents for the treatment of various diseases, particularly those related to oxidative stress and cancer.
References
Abd Elkarim, A.S., Mohamed, S.H., Ali, N.A., Elsayed, G.H., Aly M.S., Elgamal, A.M., Elsayed, W.M., and El-Newary, S.A. (2024). The Phytochemical Profile of the Petroleum Ether Extract of Purslane Leaves and Its Anticancer Effect on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-buta-4 None (NNK)-Induced Lung Cancer in Rats. Int J Mol Sci. Dec 4; 25(23), 13024. DOI: https://doi.org/10.3390/ijms252313024
Abubakar, A. R., and Haque, M. (2020). Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes. Journal of Pharmacy & Bioallied sciences, 12(1), 1–10. DOI: https://doi.org/10.4103/jpbs.JPBS_175_19
Alkali K., Dikwa K. B., Ajibade, G.A., Magaji, Y., and M.B., Abdulhamid. (2024). Qualitative and Quantitative Phytochemicals Screening of Aqueous, Methanol, and Hexane Leaves Extracts of Senna Occidentalis. Asian Plant Research Journal, Volume 12, Issue 3, Page 27-35. DOI: https://doi.org/10.9734/aprj/2024/v12i3250
Amponsah Isaac Kingsley, Mensah Abraham Yeboah, Ampofo Elikplim Kwesi, Bekoe Samuel Oppong, Sarpong Francis Mainoo, and Jibira Yakubu (2016). Pharmacognostic studies of the leaves and seeds of Cassia occidentalis (Linn.) (Leguminosae), Journal of Pharmacognosy and Phytochemistry; 5(3): 250-255.
Kumar, A. and Arya, H. (2022). Synergistic Larvicidal Action of Indigenous Plant Extracts in Combination Against Aedes aegypti (Diptera: Culicidae), Journal of Science Innovations and Nature of Earth; 2(2): 17-22.
Kumar, A. and Arya, H. (2022). Phytochemical analysis and synergistic larvicidal action of Argemone mexicana against third instar larvae of Aedes aegypti (Diptera: Culicidae), Journal of Science Innovations and Nature of Earth; 2(1): 14-20. DOI: https://doi.org/10.59436/jsiane.141.2583-2093
Kumar, A. and Arya, H. (2023). Phytochemical screening and larvicidal evaluation of leaf extract of Tinospora cordifolia against Aedes aegypti (Diptera: Culicidae), International Journal of Entomology Research: 8(4): 11-19.
Bagega, A.I., Usman, A.A., Dankaka, S.M., Amina, M., and Mani, A.U.1 (2018). Antibacterial Activity and Phytochemical Analysis of Cassia occidentalis Leaf Extract on Salmonella typhimurium, Bioremediation Science And Technology Research, Vol. 6, Page No 2, 5-8 DOI: https://doi.org/10.54987/bstr.v6i2.431
Cao, G., Sofic, E., & Prior, R. L. (2013). Antioxidant capacity of tea and common vegetables. Journal of Agricultural and Food Chemistry, 44(11), 3426-3431. DOI: https://doi.org/10.1021/jf9602535
Gupta, S. C., Tyagi, A. K., Deshmukh-Taskar, P., Hinojosa, M., Prasad, S., & Agarwal, B. B. (2014). Downregulation of tumor necrosis factor and other pro-inflammatory biomarkers by polyphenols. Archives of Biochemistry and Biophysics, 559, 91-99. DOI: https://doi.org/10.1016/j.abb.2014.06.006
Haifa A A., Omer, Giovanni Caprioli, Doaa Abouelenein, Ahmed M Mustafa, Abdullahi Ibrahim Uba, Gunes Ak, Refiye Beyza Ozturk, Gokhan Zengin, Sakina Yagi (2022). Phenolic Profile, Antioxidant, and Enzyme Inhibitory Activities of Leaves from Two Cassia and Two Senna Species. Molecules. 2022 Aug 30; 27(17): 5590. DOI: https://doi.org/10.3390/molecules27175590
Marinescu, B., Dehelean, C. A., Rusu, L. C., Gheorgheosu, D., Muntean, D., & Cinta-Pinzaru, S. (2014). A comparative study: St. John's Wort (Hypericum perforatum) and its active compounds in experimental colon cancer. Pharmaceutical Biology, 52(6), 723-730.
Ntchapda Fidèle , Barama Joseph , Azambou David Romain Kemeta, Etet Paul Faustin Seke, Dimo Théophile (2015). Diuretic and antioxidant activities of the aqueous extract of leaves of Cassia occidentalis (Linn.) in rats. Asian Pacific Journal of Tropical Medicine. Volume 8 (9), September, 685-693. DOI: https://doi.org/10.1016/j.apjtm.2015.07.030
Pandey, M. M., Rastogi, S., & Rawat, A. K. S. (2013). Indian traditional Ayurvedic system of medicine and nutritional supplementation. Evidence-Based Complementary and Alternative Medicine, 2013, Article ID 376327. DOI: https://doi.org/10.1155/2013/376327
Pandey, A. and Tripathi, S. (2014). Concept of standardization, extraction, and pre-phytochemical screening strategies for herbal drugs. Journal of Pharmacognosy and Phytochemistry, 2, 115–119.
Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., Mazur, M., & Telser, J. (2007). Free radicals and antioxidants in normal physiological functions and human disease. The International Journal of Biochemistry & Cell Biology, 39(1), 44-84. DOI: https://doi.org/10.1016/j.biocel.2006.07.001
Valsaraj, R., Pusphangadan, P., Smitt, UW, Adsensen, A., and Nyman, U. (1997): Antimicrobial screening of selected medicinal plants from India. Journal of Ethnopharmacology, Volume 58 (2), October, 75-83. DOI: https://doi.org/10.1016/S0378-8741(97)00085-8
Yadav, R. (2011). Cassia occidentalis: A review on its ethnobotany, phytochemical, and pharmacological profile. Journal of Pharmacy Research, 4(7), 2234-2240.
Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K.M., and Yoga Latha L. (2011). Extraction, isolation, and characterization of bioactive compounds from plant' extracts. Afr J Tradit Complement Altern Med. 8(1), 1-10. DOI: https://doi.org/10.4314/ajtcam.v8i1.60483
Zygmunt, J.B. and Namiesnik, J. (2003). Preparation of samples of plant material for chromatographic analysis. J Chromatogr Sci, 41, 109–116. DOI: https://doi.org/10.1093/chromsci/41.3.109
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