Assessment of Carbofuran-Induced Changes in Hepatic Lipid Parameters of Clarias batrachus over Progressive Exposure Durations
DOI:
https://doi.org/10.59436/jsiane.d2o.2583-2093Keywords:
Carbofuran, Hepatic, Lipid Parameters, Clarias batrachus, DurationsAbstract
Aquatic ecosystems are facing increasing threats from pesticide pollution, especially from carbofuran a carbamate pesticide known for its high solubility and persistence, commonly used in farming. In this study, we looked at how carbofuran impacts the liver function of Clarias batrachus, a freshwater fish often used in toxicity studies. We exposed these fish to various sublethal doses of carbofuran over different time periods (1, 7, 15, 30, 45, and 60 days) and measured changes in their lipid profiles, specifically cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL). The results showed significant increases (p < 0.05) in total cholesterol, triglycerides, and LDL levels, while HDL levels consistently dropped. This suggests that lipid metabolism was disrupted, leading to oxidative stress and liver problems. These changes can be linked to the reactive oxygen species produced when carbofuran is metabolized. Our findings indicate that Clarias batrachus is a sensitive indicator of aquatic pollution. This study highlights the urgent need for tighter environmental monitoring and regulations regarding pesticide usage to safeguard aquatic health.
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