A Review on Protective Effect of Aloevera Barbedensis on Heamatologiacal Parameters of Albino Rat after Diazinon Intoxication
DOI:
https://doi.org/10.59436/jsiane.400.2583-2093Keywords:
Diazinon toxicity, Hematological parameters, Aloe veraAbstract
The widespread use of diazinon, an organophosphate pesticide, has sparked serious worries because of its harmful effects on both humans and animals. Diazinon mainly works by blocking acetylcholinesterase, which leads to an overload of cholinergic activity, oxidative stress, and disturbances in blood parameters. Being exposed to it can result in conditions like anemia, leukocytosis, thrombocytosis, and other blood-related issues, which can hinder oxygen transport, weaken immune function, and upset the body's overall balance. Therefore, monitoring hematological parameters is crucial for evaluating toxicity. Aloe vera (Aloe barbadensis Miller), a medicinal plant packed with polysaccharides, flavonoids, anthraquinones, vitamins, and enzymes, shows impressive antioxidant, anti-inflammatory, immunomodulatory, and protective qualities. Research suggests that taking Aloe vera can help restore red blood cell counts, hemoglobin levels, and hematocrit, while also normalizing white blood cell and platelet counts, thus reducing the harmful effects of diazinon on blood health. Its ability to modulate the immune system also supports bone marrow function and boosts overall immune defense.
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