A Review on Therapeutic Evaluation of Medicinal Plants in Streptozotocin-Induced Diabetes: Impact on Haematology and Biochemical Parameters in Albino Rats
DOI:
https://doi.org/10.59436/jsiane.304.2583-2093Keywords:
Murraya koenigii, Diabetes Mellitus, Albino Rats, Therapeutic Evaluation, Medicinal Plants, Streptozotocin-Induced Diabetes, Haematology and Biochemical ParametersAbstract
The prevalence of obesity, sedentary lifestyles, and dietary changes is contributing to the long-term metabolic state known as diabetes mellitus (DM). According to the International Diabetes Federation, more than 530 million people would be living with diabetes by 2030. A significant contributor to the progression and complications of DM is oxidative stress, which leads to the breakdown of fat and impaired antioxidant defenses. In many laboratory investigations, researchers will inflict diabetes using Streptozotocin (STZ). This clarifies for them the nature of excessive blood sugar, harm to β-cells, and associated problems. Potential diabetic remedies include medicinal plants such as Pterocarpus marsupium (Indian kino tree) and Murraya koenigii (curry leaves). They are able to reduce blood sugar levels, combat oxidative stress, and promote the regeneration of β-cells. Rats with STZ-induced diabetes have shown improvement in blood sugar control, reduced oxidative stress, and insulin secretion when given these plants. To treat diabetes in a safer and more cost-effective way than with artificial medications, this review highlights the significance of medicinal plants. Because of this, integrated therapy strategies are now within reach.
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